Overview
The study aims to compare the modified approach through ipsilateral deep calf venous access of contralateral femoral venous access with the traditional approach through ipsilateral popliteal venous access for mixed type deep venous thrombosis (DVT), and determine whether it can achieve similar therapeutic effects as central type DVT.
Description
Acute deep venous thrombosis (DVT) is associated with development of post-thrombotic syndrome (PTS). Early removal of iliofemoral thrombosis by percutaneous mechanical thrombectomy (PMT) may reduce the incidence of PTS. In general, PMT is performed through ipsilateral popliteal venous access as a traditional approach. However, the thrombosis in distal popliteal vein cannot be removed. Previous study demonstrated that the residual thrombus may decrease the efficacy of PMT. The study aims to compare the modified approach through ipsilateral deep calf venous access of contralateral femoral venous access with the traditional approach for mixed type DVT, and determine whether it can achieve similar therapeutic effects as central type DVT. The purpose of this study is to obtain high-level evidence for the endovascular treatment of acute DVT.
Eligibility
Inclusion Criteria:
- Age between 18-85 years old;
- Acute DVT occurred no more than 14 days since the onset of disease;
- DVT treated by percutaneous mechanical thrombectomy
- Informed consent signed by patients.
Exclusion Criteria:
- Patients who are known to be allergic to heparin, low molecular weight heparin, or contrast agent;
- Women during pregnancy and lactation;
- Patients with other diseases that may cause difficulty in the study or significantly shorten the life expectancy of patients (<6 months);
- Patients who are unable or unwilling to participate in the study.