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A Registered Cohort Study on Spastic Paraplegia

A Registered Cohort Study on Spastic Paraplegia

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Phase N/A

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Overview

The aim of this study is to determine the clinical spectrum and natural progression of Hereditary Spastic Paraplegias(HSP) and related disorders in a prospective multicenter natural history study, to assess the clinical, genetic and epigenetic features of patients with Spastic Paraplegias to optimize clinicalmanagement..

Eligibility

Inclusion Criteria:

  • Patients with the clinical diagnosis of spastic paraplegia
  • Clinical diagnosis of patients with spastic paraplegia
  • Unrelated healthy controls

Exclusion Criteria:

  • Decline to participate.
  • There are serious interferences with individual participation and adherence to the research protocol, including but not limited to neurological, psychological, and/or medical conditions.

Study details
    Spastic Paraplegia

NCT04006418

Wan-Jin Chen

28 January 2024

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