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NUMITOR Study: Nummular Headache Iberian Study on the Treatments and Outcomes in Real-World Setting

NUMITOR Study: Nummular Headache Iberian Study on the Treatments and Outcomes in Real-World Setting

Recruiting
18 years and older
All
Phase N/A

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Overview

The NUMITOR study is an analytical observational study with an multicenter ambisective (retrospective and prospective) cohort design.

Description

This study aims to create a multicenter registry that will increase the knowledge of nummular headache and assess which treatments are more effective and better tolerated. The study population will be patients with nummular headache who, under the opinion of their responsible neurologists, have required or require preventive treatment, in any of its modalities, oral or injectable.

Eligibility

Inclusion Criteria:

  1. Nummular headache according to the criteria of the International Classification of Headache Disorders, third version (ICHD-3).
  2. Nummular headache duration of more than three months.
  3. Treatment with a medication with possible preventive drug according to the Clinical Practice Guidelines of the Spanish Society of Neurology21.
  4. Age over 18 years.
  5. Informed consent signature.

Exclusion Criteria:

  1. Diagnosis is better accounted for by any other entity included in the International Classification of Headache Disorders, 3rd version.
  2. Serious systemic or psychiatric pathology that makes it difficult to assess the patient.
  3. Secondary nummular headache
  4. Use of preventive treatment with another indication (e.g., epilepsy, other painful conditions, aesthetic).

Study details
    Headache Disorders
    Secondary
    Headache Disorders
    Central Nervous System Diseases
    Brain Diseases
    Neurologic Manifestations
    Nervous System Diseases
    Pain

NCT05475769

Hospital Clínico Universitario de Valladolid

14 October 2025

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