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The Validation and Development of Termination-of-Resuscitation (TOR) Rules in OHCA Patients in Asia Countries

The Validation and Development of Termination-of-Resuscitation (TOR) Rules in OHCA Patients in Asia Countries

Recruiting
18 years and older
All
Phase N/A

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Overview

Objectives/Hypotheses

  1. Prehospital termination-of-resuscitation (TOR) rules were developed in North American and European sites. Whether they remained valid in different geographic, ethnic, and cultural background areas is still under debate.
  2. Differences in characteristics of out-of-hospital cardiac arrests (OHCAs) and configurations of emergency medical service (EMS) between the Western and Asian countries, including relatively lower rate of presenting shockable rhythm (i.e. ventricular fibrillation / ventricular tachycardia; VF/VT), lower rates of bystander CPR, less advanced life support (ALS) implementation, and less public access defibrillators, might create potential threats to the prediction accuracy of TOR rules.
  3. We aim to conduct a study to validate the performance of ever published TOR rules in Asian OHCA population, including non-traumatic, traumatic, and pediatric OHCA patients. Furthermore, assess the possible variables that may impact the performance of TOR rules.
  4. We also aim to develop new TOR rules based on PAROS registry for Asia population, focusing on non-traumatic, traumatic, and pediatric OHCA patients, respectively.

Eligibility

Inclusion Criteria:

  • out of hospital cardiac arrest (OHCA) patients

Exclusion Criteria:

  • age <18 years
  • non-EMS transport to the emergency department
  • obvious signs of death (e.g. decapitation, rigor mortis, lividity, and decapitation) or having do-not-resuscitate (DNR) orders
  • missing data despite meeting the inclusion criteria.

Study details
    Out-Of-Hospital Cardiac Arrest

NCT05545176

National Taiwan University Hospital

28 January 2024

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