Overview
The goal of this study is compare the effect of hybrid closed loop system (HCL) for automatic insulin dosing treatment on the glycemic control of type 1 diabetes (T1D) in patient with different initial glycated hemoglobin.
Description
Rationale for the Study:
According to our hypothesis, even T1D patients with an initially optimal glucose level should benefit from this treatment method in the form of a reduction in glycemic variability.
There are very few clinical studies from real practice in a larger group of patients.
Eligibility
Inclusion Criteria:
- patients with T1D
- Type 1 diabetes for > 1 years
- ≥ 18 years old
- CSII (without HCL) or MDI
Exclusion Criteria:
- Severe noncompliance
- Known severe diabetic retinopathy and/or macular edema,
- Lactation, pregnancy, or intending to become pregnant during the study;
- A condition likely to require MRI. Use of acetaminophen-containing medication;
- Unwillingness to use the study device for >70% of time.
- Conditions that affect red blood cell turnover (hemolytic and other anemias, glucose-6-phosphate dehydrogenase deficiency, recent blood transfusion, use of drugs that stimulate erythropoesis, end-stage kidney disease).