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JS-201 Combined With Lenvatinib in the Treatment of Small-cell Lung Cancer

JS-201 Combined With Lenvatinib in the Treatment of Small-cell Lung Cancer

Recruiting
18-75 years
All
Phase 2
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Overview

This is a prospective, single-arm phase II clinical study to evaluate the efficacy and safety of JS-201 combined with lenvatinib in the treatment of small-cell lung cancer that has failed previous chemotherapy combined with PD-L1. The primary observational endpoint is ORR, and the secondary observational endpoint is PFS, OS. The intervention mode is JS201 300mg i.v Q2w, lenvatinib 8mg po. Qd.

Eligibility

Inclusion Criteria:

  • 1. The imaging diagnosis is the extensive stage of SCLC
  • 2. The patient failed first-line EC+PD-L1 treatment
  • 3 PS 0-1

Exclusion Criteria:

  • 1. Diagnosed as non-small cell lung cancer
  • 2. Women during pregnancy
  • 3. Patients with symptomatic brain metastases
  • 4. PS≥2

Study details
    Small-cell Lung Cancer

NCT04951947

Hunan Province Tumor Hospital

28 January 2024

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