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Vagal Nerve Stimulation and Pain Frequency, Intensity in Chronic Migraine

Vagal Nerve Stimulation and Pain Frequency, Intensity in Chronic Migraine

Recruiting
18 years and older
All
Phase N/A

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Overview

This study is being conducted to address the need for effective and well-tolerated interventions in preventing chronic migraine attacks. Chronic migraines significantly impact the quality of life for individuals suffering from them, often leading to substantial discomfort and impairment. By evaluating the feasibility, safety, and acceptance of noninvasive vagus nerve stimulation (nVNS), researchers aim to determine if this approach can offer a viable solution for alleviating the frequency and severity of chronic migraine episodes. If successful, this study could potentially introduce a promising new treatment option that enhances the well-being and daily functioning of those affected by chronic migraines.

Description

Neuromodulation is a growing field in headache management. Technology ranges from invasive deep brain stimulation (DBS) of the posterior hypothalamus, to minimally invasive percutaneous electrode implantation for occipital nerve stimulation, and noninvasive transcranial magnetic stimulation and transcranial direct current stimulation. Neurostimulation can be particularly useful to those who failed triptans or other prophylactic treatments. The European Headache Federation positioned that a neurostimulation device should only be used in medically intractable headache patient who has been evaluated at a tertiary headache center. Vagus nerve stimulation (VNS), which has demonstrated its antinociceptive potential, may also provide a relief of pain associated with headache

Eligibility

Inclusion Criteria:

  • Chronic migraine (headache for 15 or more days/month for more than three months), Migraine with/without aura

Exclusion Criteria:

  • Mental illness, Photophobic individual, Presence of shunt and/or implant at the cranial region

Study details
    Migraine

NCT06191016

Riphah International University

29 January 2024

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