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RCT for the Efficacy of Soothing Cream Jel in Improving Upper Limb Pain and Motion

RCT for the Efficacy of Soothing Cream Jel in Improving Upper Limb Pain and Motion

Recruiting
18-60 years
All
Phase 2

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Overview

This is a randomized, double-blinded, placebo-controlled clinical trial. This trial is used to evaluate the efficacy of soothing cream jel on chronic upper limb pain and the range of motion.

Description

Potential subjects will be screened according to the eligibility criteria after signing the informed consent form. Subjects who fulfill the requirements will be randomized into either the treatment group or the placebo group. And receive either soothing cream jel or placebo cream jel for 2 weeks. Then followed by a post-treatment for 2 weeks.

Eligibility

Inclusion Criteria:

  1. Age 18-60;
  2. Participates in regular physical activity, at least once a week for 30 minutes;
  3. Chronic pain in the shoulder or elbow longer than 3 months;
  4. 11-items Numeric pain rating scale ≥4; and
  5. Willing to provide written informed consent.

Exclusion Criteria:

  1. The patient had received previous physiotherapy, acupuncture, Tui Na massage, or bone-setting treatment for distal upper limb pain within the past 2 weeks;
  2. The pain was due to a fracture or known complex regional pain syndrome.
  3. History of upper limb surgery;
  4. Known severe medical conditions (e.g. rheumatoid arthritis, osteoporosis, cardiac, renal, hepatic, hematological diseases, vertigo, seizure, infection, malignancy, neurological impairment);
  5. Concomitant drugs of NSAIDs, any kind of painkillers, or anti-inflammatory drugs 15 days prior to randomization;
  6. Known impaired hematological profile and liver / renal function;
  7. Known allergic history to any topical cream;
  8. Known pregnant or lactating; or
  9. Unable to complete questionnaires

Study details
    Upper Extremity Problem

NCT05799391

Chinese University of Hong Kong

19 May 2024

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FAQs

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What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

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The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

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