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Mass Response of Tumor Cells as a Biomarker for Rapid Therapy Guidance (TraveraRTGx)

Mass Response of Tumor Cells as a Biomarker for Rapid Therapy Guidance (TraveraRTGx)

Recruiting
18 years and older
All
Phase N/A

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Overview

The primary objective of this study, sponsored by Travera Inc. in Massachusetts, is to validate whether the mass response biomarker has potential to predict response of patients to specific therapies or therapeutic combinations using isolated tumor cells from various specimen formats including malignant fluids such as pleural effusions and ascites, core needle biopsies, fine needle aspirates, or resections.

Eligibility

Inclusion Criteria:

  1. Patient is ≥18 years of age
  2. Written Informed Consent provided by patient
  3. Diagnosis of any kind of carcinoma
  4. Malignant fluid (e.g. pleural effusion or ascites) drainage OR tumor tissue resection OR tumor tissue needle biopsy is clinically indicated as part of SOC
  5. Proceeding onto therapy for treatment
  6. Informed consent obtained for the XCELSIOR longitudinal outcomes registry (NCT03793088)

Exclusion Criteria:

  1. Lack of informed consent
  2. Unable to obtain sufficient sample

Study details
    Pleural Effusion
    Malignant
    Ascites
    Malignant
    Carcinoma
    Carcinoma
    Hepatocellular
    Carcinoma
    Renal Cell
    Carcinoma
    Renal
    Carcinoma
    Small Cell
    Carcinoma
    Non-Small-Cell Lung
    Carcinoma
    Pancreatic Ductal
    Carcinoma
    Neuroendocrine
    Carcinoma
    Thymic
    Carcinoma
    Pancreatic
    Carcinoma Breast
    Carcinoma
    Ovarian
    Carcinoma Bladder
    Carcinoma of Unknown Primary
    Carcinoma of the Head and Neck
    Carcinoma of the Oropharynx
    Carcinoma of the Larynx
    Carcinoma of the Bladder
    Carcinoma of Esophagus
    Carcinoma of the Nasopharynx
    Carcinoma of the Penis
    Carcinoma of the Cervix
    Carcinoma of the Anus
    Carcinoma of the Vulva
    Carcinoma of the Appendix
    Carcinoma of the Oral Cavity
    Cholangiocarcinoma
    Melanoma
    Mesothelioma
    Pancreatic Cancer

NCT05461430

Travera Inc

28 January 2024

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