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Efficacy and Safety of Auto-FMT in Preventing aGVHD

Efficacy and Safety of Auto-FMT in Preventing aGVHD

Recruiting
18-60 years
All
Phase N/A

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Overview

To evaluation the efficacy and safety of autologous fecal bacteria transplantation in preventing acute graft versus host disease after haploidentical hematopoietic stem cell transplantation. Bone marrow transplant patients were recruited.

Eligibility

Inclusion Criteria:

  • Haplo-HSCT patients; Bacteroidetes >0.1%; inverse Simpson diversity ≥2

Exclusion Criteria:

  • Gastrointestinal diseases;Age>60; or Age<10;Probiotics or prebiotics were taken before enrollment

Study details
    Graft Versus Host Disease
    Acute

NCT04745221

The First Affiliated Hospital of Soochow University

18 April 2024

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