Overview
There is no information in the literature on the mechanobiological characteristics of mitral valve chords in living humans. All examinations were carried out on tissues taken from animals, either from cadavers or from frozen human tissues. The objective is to determine mechanobiological and histological characteristics of the mitral valve chords in living humans, as well as to compare differences in elasticity in different groups (Group A: patients with mitral valve prolapse versus Group B: patients with restrictive ischemic mitral valve).
Description
The prospective study will be conducted on 20 patients, who will be selected consecutively without randomization. The inclusion and exclusion criteria are determined.
The harvested tissue will not be frozen and will kept in natural conditions as close as possible.
Eligibility
Inclusion Criteria:
All patients programmed for mitral valve replacement who have more than 45 years old
Exclusion Criteria:
- Patients with mitral calcification
- Mitral valve rheumatic disease
- Mitral valve infections
- Redo surgery on the mitral valve