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Evaluation of Heart Status in Patients of Beta Thalassemia Using Echocardiogram

Evaluation of Heart Status in Patients of Beta Thalassemia Using Echocardiogram

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Overview

Heart failure from myocardial iron deposition is a severe complication for patients with transfusion-dependent beta thalassemia . Increased cardiac iron content impacts the contractility of cardiomyocytes and can also lead to myocarditis, pericarditis, and arrhythmias. The severity of cardiac dysfunction depends on the amount of iron deposited in the myocardium.Echocardiogram is used as noninvasive method to observe heart status. The objective of this study is to evaluate the heart status in patients of Beta Thalassemia from southern China.

Eligibility

Inclusion Criteria:

  • Diagnosed with beta-thalassemia

Exclusion Criteria:

  • Iron deficiency anemia

Study details
    Beta Thalassemia

NCT04929574

Nanfang Hospital, Southern Medical University

28 January 2024

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