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Juvenile Recurrent Respiratory Papillomatosis: Establishment of a French National Cohort (PRR : National Cohort " REPA ")

Juvenile Recurrent Respiratory Papillomatosis: Establishment of a French National Cohort (PRR : National Cohort " REPA ")

Recruiting
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Phase N/A

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Overview

Recurrent respiratory papillomatosis (RRP) is a rare disease. However, it is the most common benign laryngeal tumor in children. To date, no epidemiological data are available in France. The aim of this study is to establish the epidemiology of juvenile PPR.

Description

Recurrent respiratory papillomatosis (RRP) is characterized by the recurrent proliferation of multiple polypoid squamous tumors in the respiratory tract, linked to HPV infection. RRP is a rare disease. However, it is the most common benign laryngeal tumor in children.

There are currently no French national epidemiological data on this disease. The data collected by the reference centers will enable us to gain a better understanding of this pathology in terms of epidemiology, risk factors, genetic susceptibility and clinical manifestations, as well as to significantly study the efficacy of the various existing therapies and preventive measures, in order to establish a clear, standardized and optimal guideline.

Eligibility

Inclusion Criteria:

  • Patients with juvenile PRR (disease onset before age 18)
  • Followed in the :
    • The MALO CRMR
    • One of the MALO network's CCMRs
    • One of the main correspondent centers

Exclusion Criteria:

  • Patients objecting to the collection of their personal data
  • Parents of minor patients objecting to the collection of their child's personal data

Study details
    Juvenile Recurrent Respiratory Papillomatosis

NCT06000527

Imagine Institute

28 January 2024

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