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A Study of Low and Standard-dose Ticagrelor After Intervention for ACS Patients

A Study of Low and Standard-dose Ticagrelor After Intervention for ACS Patients

Recruiting
18-90 years
All
Phase 4

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Overview

This study is to evaluate the safety and efficacy of 60mg ticagrelor plus 100mg Aspirin to prevent major adverse cardiovascular and cerebrovascular events in one years after drug-eluting stents implantation for Chinese ACS patients compared with 90mg ticagrelor plus 100mg Aspirin

Eligibility

Inclusion Criteria:

  1. Subject must be at least 18 years of age
  2. Patients should have undergone successful percutaneous coronary intervention with drug-eluting stent for acute coronary syndrome
  3. Subject understand the study requirements and the treatment procedures and provided informed consent before the procedure

Exclusion Criteria:

  1. Female of childbearing potential, unless a recent pregnancy test is negative, who possibly plan to become pregnant any time after enrollment into this study
  2. Active bleeding
  3. Known hypersensitivity or contraindication to study medications
  4. Non-cardiac co-morbid conditions are present with life expectancy <2 year or that may result in protocol non-compliance (per site investigator's medical judgment).
  5. Subjects with Cerebral hemorrhage history
  6. Subjects with stroke history in half a year
  7. subjects with malignant tumor
  8. subjects with whom oral anticoagulants are needed

Study details
    Acute Coronary Syndrome
    Coronary Stent Implantation

NCT04255602

Shanghai Tong Ren Hospital

28 January 2024

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FAQs

Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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