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Danish Angle Closure Prevention Trial

Danish Angle Closure Prevention Trial

Recruiting
40-80 years
All
Phase N/A
  • Technical (Original)
  • Simplified (AI rewritten)

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Overview

To determine whether primary angle closure suspects (PACS) in a Caucasian population benefit from prophylactic laser iridotomy.

Description

Prospective, randomised paired-eye design clinical trial comparing peripheral laser iridotomy in one eye with observation in the other over 5-years follow-up.

Eligibility

Inclusion Criteria:

  • Primary angle closure suspect: ≥180 degrees (cumulative) irido-trabecular contact on darkroom gonioscopy, IOP<21mmHg, no peripheral anterior synechiae, no glaucomatous optic neuropathy
  • Best-corrected visual acuity (BCVA) >0.8 on both eyes
  • Caucasian

Exclusion Criteria:

  • Pseudophakia
  • Previous iridotomy
  • Clinically significant cataract with indication for surgery,
  • Gaucoma
  • Uveitis
  • Unstable retinal conditions
  • Ocular malignancies
  • PEX
  • PDS
  • Systemic or ocular corticosteroid treatment

Study details
    Primary Angle Glaucoma Closure Suspect

NCT06077253

University of Aarhus

28 January 2024

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