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Arterial Spin Labeling MRI for Assessing Blood Perfusion in the Human Eye Repeatability Study and Clinical Application

Arterial Spin Labeling MRI for Assessing Blood Perfusion in the Human Eye Repeatability Study and Clinical Application

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18 years and older
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Phase N/A
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Overview

The MRI perfusion imaging using arterial spin labeling (ASL)'s non-invasive technique (i.e. without injection of contrast medium) allows, thanks to recent technological improvement of the spatial resolution, measuring several perfusion parameter of the retinal tissue such as the regional Blood Flow (rBF) or the cerebral blood flow (cBF) expressed in ml/100g/min. Reliable application of ASL thus requires the precision and specificity of the MRI protocol to be tested.

Eligibility

Inclusion criteria:

  • Carrier of target pathologies: TAO optic neuropathy, inflammatory optic neuropathy, ischemic optic neuropathy.
  • no cardiovascular risk factors or other ophthalmological pathology
  • adhere to the study protocol after reading the patient information document
  • signe the informed consent form to participate in the study
  • do not have any contraindications to an MRI examination

Exclusion criteria

  • Usual contraindications to MRI (Pacemaker, Metallic foreign body, Cochlear implant,…)
  • Severe claustrophobia

Study details
    Retinal Diseases

NCT05724641

Cliniques universitaires Saint-Luc- Université Catholique de Louvain

18 April 2024

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