Overview
The purpose of this experiment is to evaluate the efficacy of Closed-loop Functional Spinal Cord Stimulation on Walking Rehabilitation in Patients after Spinal Cord Injury
Description
The whole course will last around 12 months, during which there will be: Pre-implant evaluations and standard rehabilitation (6-10 weeks), Stimulator implantation and stimulation optimization (4-8 weeks), Rehabilitation training with stimulation (6 months). At the end of the protocol, the study aims to make the patients walk better and faster.
Eligibility
Inclusion Criteria:
- Age 18~70
- Spinal cord injury staging(AIS) A,B,C or D
- Level of lesion is T10 and above
- Distance between lesion and conus >60mm
- Injured Time > 3 months
- Capable of participating rehabilitation program
- Agree to comply with all conditions of the study and to attend all required study training and visits
Exclusion Criteria:
- With Obvious psychiatric disorder that cannot complete relevant questionaires
- Cognitive impairment
- Severe autonomic reflex disorder
- Severe muscle atrophy and joint contracture
- Cannot participate in spinal cord stimulation surgery or follow-up visits
- Life expectancy less than 12 months
- Abnormal blood or other physiological examinations that cannot conduct surgery, such as blood coagulation disorder or kidney/liver abnormalities
- Uncontrollable hypertension, heart diseases, respiratory diseases or took related medicine in last 3 months
- Unsuitable candidates in PI's perspective