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Non-Invasive Characterization of Focal Liver Lesions in Liver Cirrhosis

Non-Invasive Characterization of Focal Liver Lesions in Liver Cirrhosis

Recruiting
18-99 years
All
Phase N/A

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Overview

This study aims to analyze non-invasive characterization focal liver lesions in patients with liver cirrhosis. The diagnostic accuracy and predictive value of non-invasive methods is studied.

Description

This study aims to analyze non-invasive characterization focal liver lesions in patients with liver cirrhosis. The diagnostic accuracy and predictive value of non-invasive methods is studied.

Upon diagnosis multiparametric ultrasound imaging of the lesions as well as sarcopenia parameters are performed for characterization of the lesions. For primary endpoint the results are then analyzed with regard to diagnostic accuracy compared to gold standard (CT, MRI or histology). For secondary endpoint, predictive value of the non-invasive diagnostics are analyzed with regards to mortality and response to treatment.

All work up, treatment and follow up are applied in standard of care fashion.

Eligibility

Inclusion Criteria:

  • all patients with focal liver lesions and liver cirrhosis

Exclusion Criteria:

  • no consent
  • under 18 years

Study details
    Liver Cirrhoses

NCT03746210

University Hospital, Bonn

27 January 2024

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