Image

Cardiac Function and Exercise Capacity in Pulmonary Arterial Hypertension

Cardiac Function and Exercise Capacity in Pulmonary Arterial Hypertension

Non Recruiting
18 years and older
All
Phase N/A

Powered by AI

Overview

Pulmonary Arterial Hypertension is characterized by a progressive increase in pulmonary vascular resistance inducing shortness of breath and exercise intolerance. We aim to correlate cardiac function (evaluated at rest by right heart catheterism and RMN) to exercise capacity (evaluated by endurance time at 75% of maximal workout), in prevalent patients with pulmonary arterial hypertension, and their evolution at three and twelve months.

Eligibility

Inclusion Criteria:

  • Adult patients
  • Patients with Pulmonary Arterial Hypertension (idiopathic, heritable or due to anorexigens),
  • Prevalent cases of pulmonary artery hypertension (≥ 6 months) confirmed by right heart catheterism,
  • Stable for at least 3 months,
  • Written consent.

Exclusion Criteria:

  • Patients unable to proceed with six-minute walk test or CPET, or with contra-indication to exercise evaluation (syncope, low cardiac index, etc).
  • Exercise induced abnormality (evaluated during the initial CPET) precluding to further evaluation.

Study details
    Pulmonary Arterial Hypertension

NCT02579954

Centre Hospitalier Universitaire de Saint Etienne

20 August 2025

FAQs

Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
Add a private note
  • abc Select a piece of text.
  • Add notes visible only to you.
  • Send it to people through a passcode protected link.