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Percutaneous Needle Fasciotomy +/- Corticosteroid Injection for Dupuytren's Contracture

Percutaneous Needle Fasciotomy +/- Corticosteroid Injection for Dupuytren's Contracture

Recruiting
45-99 years
All
Phase 4
  • Technical (Original)
  • Simplified (AI rewritten)

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Overview

Comparing percutaneous needle fasciotomy +/- corticosteroid injection for Dupuytren's contracture affecting metacarpophalangeal joints. A clinician-initiated, multicenter, randomized controlled trial.

Eligibility

Sufficient correction of metacarpophalangeal (MCP) joint during the PNF treatment, defined

as <20° passive extension deficit (PED), is a prerequisite for inclusion.

Inclusion Criteria:

  • Dupuytren contracture (DC) of ≥ 20° PED in MCP joint measured with a goniometer
  • DC of either II-V finger
  • Well-defined/palpable cord

Exclusion Criteria:

  • Legally incapacitated
  • Previous study inclusion with another finger ray
  • Isolated proximal interphalangeal (PIP) or distal interphalangeal (DIP) joint contracture, defined as MCP joint contracture < 20° PED regardless of the deficit in the PIP or DIP joint
  • Previous hand surgery of the affected finger for any reason
  • Known allergy to the study medication
  • Anticoagulant therapy (Acetylsalicylic acid is NOT an exclusion criterion)
  • Pregnant or lactation
  • Insulin dependent diabetes mellitus
  • Ongoing systemic infection or local infection at the site of the procedure
  • Rheumatoid arthritis
  • Amyloidosis or mucopolysaccharidosis
  • Unable to communicate, cooperate or participate in follow-up

Study details
    Dupuytren Contracture
    Dupuytren's Disease
    Contracture
    Joint Diseases
    Musculoskeletal Diseases
    Fibroma
    Neoplasm
    Fibrous Tissue
    Neoplasms
    Connective Tissue
    Neoplasms
    Connective and Soft Tissue
    Neoplasms by Histologic Type
    Neoplasms
    Connective Tissue Diseases

NCT05440240

Regionshospitalet Silkeborg

27 January 2024

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