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Inhibitory Control: Effects of Modulation

Inhibitory Control: Effects of Modulation

Recruiting
18-25 years
All
Phase N/A

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Overview

Inhibitory control is relevant to many clinical disorders, including substance abuse/dependence, obsessive-compulsive disorder, and attention-deficit hyperactivity disorder. This proposal is designed to assess brain networks related to response inhibition in healthy young adults, and use neuromodulation to change these networks and behavioral performance on a response inhibition task. Having an understanding of the brain mechanisms involved in response inhibition may enable us to improve pre-existing treatments for disorders with inhibitory control difficulties.

Eligibility

Inclusion Criteria:

  1. Low (<1sd below the mean on the BRIEF-Inhibit) or high (>1sd above the mean on BRIEF-Inhibit scale)
  2. English fluency to ensure comprehension of study measures and instructions.

Exclusion Criteria:

  1. Presence of medical conditions contraindicated for tDCS, including history of any known intracranial pathology, epilepsy or seizures, traumatic brain injury, brain tumor, stroke, implanted medical devices, current pregnancy or women of childbearing age not using effective contraception, or any other serious medical conditions or health problems that would interfere with participation (e.g., skin condition)
  2. Inability to undergo MRI
  3. Current substance abuse disorder
  4. Currently prescribed psychiatric medications.
  5. Active mania or psychosis

Study details
    Young Adults

NCT04247334

Butler Hospital

27 January 2024

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