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Different Modalities of Management of Odontogenic Keratocysts

Different Modalities of Management of Odontogenic Keratocysts

Recruiting
10 years and older
All
Phase N/A

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Overview

Background The odontogenic keratocysts (OKCs) have been one of the maxillofacial region's most contentious pathological phenomena. Decompression/marsupialization (D/M), enucleation (E), enucleation + chemical cauterization with Carnoy's solution (E+CS), enucleation + peripheral ostectomy (E + PO), as opposed to enucleation + chemical cauterization with Carnoy's solution + peripheral ostectomy (E + CS + PO), were used during surgery to ensure that no epithelial remnants were left behind.

Rationale Through the management of OKC a recurrence could occur, the effectiveness of Decompression/marsupialization (D/M), Enucleation (E), Enucleation+Carnoy's solution chemical cauterization (E+CS), Enucleation+peripheral ostectomy (E+PO), Enucleation+Carnoy's solution chemical cauterization + peripheral ostectomy (E+CS + PO), will be analyzed

Description

Since the middle of the 20th century, the odontogenic keratocyst (OKC) has been one of the maxillofacial region's most contentious pathological phenomena. It was initially misdiagnosed as a primordial cyst. After that, because of its severe clinical behavior and tendency to recur, it was no longer considered to be a part of its classification, also known as a odontogenic tumor. Then, In 2017, the OKC are re-classified as a cystic lesion. But still there is debate about their management. So, this study will be enrolled with the following objectives: to describe how odontogenic keratocysts are managed, to Discover the most favorable approach to manage OKC with the need to stop it from happening again To categorize the odontogenic keratocyst management outcomes into to the subsequent groups: (1) total resolution, (2) partial resolution; (3) Recurrence.

Eligibility

Inclusion Criteria:

  • All odontogenic keratocysts that are treated by the following surgical treatment
    modalities
    1. Enucleation followed by peripheral ostectomy and Carnoy's solution
    2. Decompression/ marsupialization
    3. Enucleation
    4. Enucleation and Carnoy's solution
    5. Enucleation and Peripheral Ostectomy
  • Follow-up period 10 years

Exclusion Criteria:

  • Cases treated with resection
  • Cases showed neoplastic transformation in their pathology
  • Cyst Like lesions

Study details
    Odontogenic Cysts

NCT06133764

Qassim University

27 January 2024

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