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Rebooting Infant Pain Assessment: Using Machine Learning to Exponentially Improve Neonatal Intensive Care Unit Practice

Rebooting Infant Pain Assessment: Using Machine Learning to Exponentially Improve Neonatal Intensive Care Unit Practice

Recruiting
27-33 years
All
Phase N/A

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Overview

A multi-national multidisciplinary team will be working collaboratively to build a machine learning algorithm to distinguish between preterm infant distress states in the Neonatal Intensive Care Unit.

Description

Unmanaged pain in hospitalized infants has serious long-term complications. Our international team of knowledge users and health/natural science/engineering/social science researchers have come together to build a machine learning algorithm that will learn how to discriminate invasive and non-invasive distress. A sample of 400 preterm infants (300 from Mount Sinai Hospital and 100 from University College London Hospital [UCLH]) and their mothers will be followed during a routine painful procedure (heel lance). Pain indicators (facial grimacing [behavioural indicators], heart rate, oxygen saturation levels [physiologic indicators], brain electrical activity) during the painful procedure will be used to train the algorithm to discriminate between different types of distress (pain-related and non-pain related).

Eligibility

  • QUALITATIVE INTERVIEWS
    • Inclusion Criteria:
    • parents of a child currently in the NICU or
    • health professionals currently working in the NICU.
    • Exclusion Criteria:
    • Participants who cannot communicate fluently in English
    • QUANTITITATIVE DATA CAPTURE (video, eeg, ecg, SPo2)
    • Inclusion Criteria:
    • Infants born between 28 0/7 weeks 32 6/7 weeks gestational age
    • Infants who are within 6 weeks postnatal age
    • Infants who are undergoing a routine heel lance
    • Exclusion Criteria:
    • Infants with congenital malformations
    • Infants receiving analgesics or sedatives at the time of study (aside from sucrose),
    • Infants with history of perinatal hypoxia/ischemia at the time of study.
    • Infants with diaper rash or excoriated buttocks

Study details
    Acute Pain

NCT05579496

York University

27 January 2024

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