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Assessing Benefits of Near Infrared Autofluorescence (NIRAF) Detection for Identifying Parathyroid Glands During Total Thyroidectomy

Recruiting
18 years of age
Both
Phase N/A

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Overview

This study will see if the use of near infrared autofluorescence (NIRAF) detection with a 'Parathyroid Eye (PTeye)' for identifying parathyroid glands (PGs) during total thyroidectomy (TTx) is better than surgeon's detection alone. It compares risk, benefits and outcomes in TTx patients where NIRAF detection with PTeye for parathyroid identification is either used or not used.

Eligibility

Inclusion Criteria:

  • Patients with thyroid disease who will be undergoing total thyroidectomy (includes patients who have undergone a prior neck exploration for parathyroid disease or other but have an intact thyroid gland).
  • Patients with persisting thyroid disease and will be undergoing re-operative or completion thyroidectomy.

Exclusion Criteria:

  • Pregnant women
  • Patients with concurrent parathyroid and thyroid disease
  • Patients with incidental enlarged parathyroid discovered during thyroidectomy procedure.
  • Patients undergoing thyroid lobectomy or partial thyroidectomy

Study details

Thyroid Neoplasms, Thyroid Diseases, Hypoparathyroidism, Endocrine System Diseases, Endocrine Gland Neoplasms

NCT05022667

University of Michigan

27 January 2024

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