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Monitoring of MDRO Dynamics and Resistance Mechanisms in a University Hospital Network

Monitoring of MDRO Dynamics and Resistance Mechanisms in a University Hospital Network

Recruiting
18 years and older
All
Phase N/A

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Overview

Survey on the prevalence of MDRO to monitor the import of MDRO from the community. Rectal swabs will be taken and cultivated. Survey on community-onset and nosocomial bloodstream infections will be documented and strains will be isolated. For each BSI a clinical data set will be obtained (e.g. patient age, gender, date of hospitalization, antibiotic therapy). Genetic analysis of MDRO from the prevalence and BSI study. In a subset of patients the microbiome-resistome interactome will be analysed in more detail. Furthermore, the impact of infection control measures due to the Covid-19 pandemic on nosocomial BSI will be investigated.

Eligibility

Inclusion Criteria:

  • at least 18 years old
  • informed consent
  • inpatient

Exclusion Criteria:

  • less than 18 years old
  • Not capable of giving informed consent
  • outpatient

Study details
    MDRO

NCT04937361

University of Luebeck

27 January 2024

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