Overview
The purpose of this study is to investigate the effects of acute inorganic nitrate supplementation (with beetroot) on the regulation of sleep and neurovascular physiology.
Eligibility
Inclusion Criteria:
- 18-30 or 65-80 years of age
Exclusion Criteria:
- Coronary artery disease
- Heart failure
- Pregnancy
- Diabetes
- Sleep disorders
- Shift workers
- Individuals who typically go to sleep after midnight
- Individuals who traveled across ≥2 time zones within one week of study visits
- Individuals with a history frequent kidney stones
- BMI ≥35.0kg/m2
- Use of nicotine-containing products within the two years preceding study visits
- Use of allopurinol, proton pump inhibitors, or other medications/supplements which interfere with the nitrate-nitrite-nitric oxide pathway or outcome measures