Overview
To define the effect of crystal light, potassium citrate, or both on urinary stone risk factors in patients with a history of stone and hypocitraturia/low pH
Eligibility
Inclusion Criteria:
- Men and women between age 18-80 years
- Willing to follow experimental protocol
- Willing to complete 24-hour urine collections (three total)
- Willing to sign the informed consent form
- Completed Litholink Collection with blood work with results
- hypocitraturia OR aciduria i. Hypocitraturics must meet definition of < 450 mg/day for men < 550 mg/day for women.
- Low urine pH must be less than 5.6 c. potassium, BUN, creatinine, eGFR and hemoglobin A1c within normal limits
Exclusion Criteria:
- Patients with severe hypocitraturia < 200 mg/day (men or women)
- Patients with hyperkalemia, uncontrolled diabetes, chronic kidney disease, adrenal insufficiency, delayed gastric emptying (or drug induced delayed gastric emptying), peptic ulcer disease, or active UTI
- Patients with distal renal tubular acidosis or medication induced RTA (e.g. carbonic anhydrase inhibitor, topiramate)
- Members of vulnerable patient populations
- Allergies to ingredients in crystal light
- Patients lacking decisional capacity