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Clinical Evaluation of Visual Field Change in Glaucoma: an Assessment of Different Models of Progression

Clinical Evaluation of Visual Field Change in Glaucoma: an Assessment of Different Models of Progression

Recruiting
40-90 years
All
Phase N/A

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Overview

The purpose of this observational study is to collect over time a series of data in patients with glaucoma in order to evaluate different approaches in defining the progression of this pathology. These data will be collected in repeated visits over a 36-months follow-up period. At each visit, the COMPASS fundus perimeter and the Humphrey Field Analyzer (HFA) perimeter will be used to assess retinal functionality; an Optical Coherence Tomography (OCT) examination will also be performed to evaluate and obtain clinical information about the structure of the retina.

Eligibility

Inclusion Criteria:

  • Glaucomatous optic nerve head in both eyes;
  • Age between 40 and 90 years;
  • Best Corrected Visual Acuity ≤ 0.3 [logMar];
  • Spherical refraction between -6D and +6D;
  • Astigmatism between -2D and +2D.

Exclusion Criteria:

  • Any ocular surgery, except for: uncomplicated cataract surgery and/or glaucoma surgery in both eyes performed within 6 months before enrollment;
  • Any ocular pathology that can affect visual field other than glaucoma;
  • Use of any drug that can interfere with the correct execution of perimetry or that would produce visual field loss;
  • Inability to obtain reliable perimetric examinations;
  • Patients with advanced glaucoma for whom, according to the clinician, a 24-2 grid is not advisable to correctly monitor the patient.

Study details
    Glaucoma

NCT05801471

Centervue SpA

27 January 2024

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