Overview
To investigate the effect on cognition under sedation by Rimazole toluenesulfonatein elderly patients undergoing colonoscopy
Eligibility
Inclusion Criteria:
- ASA I~II
- patients will be treatmented by sedation under colonoscopy
- sign informed consent
Exclusion Criteria:
(1) Preoperative depression and cognitive impairment
(2) Hearing or visual impairment;
(3) Drug abuse, alcoholism or long-term use of antidepressants;
(4) Cardiovascular and cerebrovascular accidents, neurological sequelae, or severe liver
and kidney function damage occurred within 6 months
(5) BMI < 18, BMI > 30
(6) Confirmed or suspected allergy to the test drug