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Novel Approaches to Target MECOM/EVI1 in AML

Recruiting
18 years of age
Both
Phase N/A

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Overview

This is an academic, no-profit, multicenter, biological, non-pharmacologic study aimed at characterizing genome, transcriptome and proteome of patients affected by AML with MECOM or atypical 3q26 rearrangements.

Description

This is an academic, no-profit, multicenter, biological, non-pharmacologic study aimed at characterizing genome, transcriptome and proteome of patients affected by AML with MECOM or atypical 3q26 rearrangements. To this end, BM samples and formalin fixed/paraffin-embedded BM biopsies will be collected at enrolment, before and after treatment, at relapse.

Eligibility

Inclusion Criteria:

  • AML with MECOM or atypical 3q26 rearrangements.
  • Age ≥18.
  • Signed written informed consent according to ICH/EU/GCP and national local laws.

Exclusion Criteria:

  • None

Study details

AML, Adult

NCT05839392

Gruppo Italiano Malattie EMatologiche dell'Adulto

27 January 2024

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