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Descartes-08 CAR-T Cells in Generalized Myasthenia Gravis (MG)

Descartes-08 CAR-T Cells in Generalized Myasthenia Gravis (MG)

Non Recruiting
18 years and older
All
Phase 2

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Overview

This is a Phase IIb study to evaluate the safety and preliminary efficacy of Descartes-08 CAR T-cells in patients with Generalized Myasthenia Gravis

Eligibility

Inclusion Criteria:

  • Patient must be at least 18 years of age.
  • Patient must have Generalized Myasthenia Gravis at the time of screening.
  • Concomitant immunosuppressive drugs must be deemed necessary by the investigator.
  • Seronegative Patients are included

Exclusion Criteria:

  • Major chronic illness that is not well managed at the time of study entry and in the opinion of the investigator may increase the risk to the patient.
  • Patient is pregnant or lactating.

Study details
    Myasthenia Gravis
    Generalized

NCT04146051

Cartesian Therapeutics

20 August 2025

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Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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