Overview
In this interventional clinical trial, researchers will administer electroacupuncture versus sham electroacupuncture to sepsis patients with ARDS and collect objective outcome measures. The study will be divided into 2 groups. The EA group will receive electroacupuncture and the SHAM-EA group will receive sham electroacupuncture. The purpose of this study is to investigate the effect of electroacupuncture on the synthesis of SPMs in sepsis patients with ARDS.
Eligibility
Inclusion Criteria:
- Males or females over the age of 18;
- Diagnosis meets SPESIS 3 criteria for sepsis;
- The diagnosis meets the Berlin diagnostic criteria for ARDS;
- ARDS was diagnosed within 48h;
- Capable of understanding the purpose and risk of the study;
- Patients or proxy must give written informed consent before any assessment is performed.
Exclusion Criteria:
- ARDS was diagnosed 48h later;
- Pregnancy, lactation or perinatal period;
- malignant tumor;
- Severe liver failure or kidney failure;
- Predicted mortality risk of patients within 24h>80%;
- Severe end-stage lung disease;
- ECMO patients are undergoing implementation;
- HIV seropositive or Syphilis seropositive;
- Any clinical-relevant condition that might affect study participation and/or study results;
- Participation in any other intervention trial;
- Unwillingness or inability to following the study protocol in the investigators opinion.