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Influenza Associated Aspergillosis In-depth Investigation

Influenza Associated Aspergillosis In-depth Investigation

Recruiting
18 years and older
All
Phase N/A
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  • Simplified (AI rewritten)

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Overview

This trial is aimed to study the immunological and pathological characteristics of influenza versus non-influenza severe community-acquired pneumonia patients in ICU.

Description

This trial is aimed to study the immunological and pathological characteristics of influenza versus non-influenza severe community-acquired pneumonia patients in ICU, and correlate findings with occurrence of secondary invasive pulmonary aspergillosis infection.

All consecutive patients aged 18 or older admitted to ICU during the inclusion period with respiratory distress due to influenza positive/negative community acquired pneumonia (CAP) will be included.

Eligibility

Inclusion Criteria:

  • All patients older than 18 years, admitted to ICU with respiratory distress with microbiologically confirmed diagnosis of influenza (for inclusion in the influenza group)
  • All patients older than 18 years, admitted to ICU for respiratory distress due to community- acquired pneumonia , with a microbiologically confirmed absence of influenza (for inclusion in the control group)

Exclusion Criteria:

  • Age < 18 years old
  • Pregnant women
  • No informed consent

Study details
    Influenza With Pneumonia
    Invasive Pulmonary Aspergillosis

NCT03748069

Universitaire Ziekenhuizen KU Leuven

27 January 2024

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