Overview
The goal of this observational study is to investigate the proportion of Mycobacterium tuberculosis (MTB) infection in school contacts of active tuberculosis (ATB) patients. The main questions it aims to answer are:
- the proportion of MTB infection among school contacts of ATB patients
- risk factors related to tuberculosis (TB) infection
- health economic evaluation of screening strategy
Eligibility
Inclusion Criteria:
- 13 years old or above;
- Students in junior middle school, high school and university;
- Close contact of school active tuberculosis case (e.g. in the same classroom, in the same dormitory);
- Himself/herself (together with his/her guardian for age under 18 years old) willing to participate in trial and sign informed consent.
Exclusion Criteria:
- Current clinical or sputum culture confirmed active tuberculosis
- Have completed a full course of treatment for ATB or LTBI