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Methocarbamol in Ventral and Inguinal HR

Methocarbamol in Ventral and Inguinal HR

Non Recruiting
18 years and older
All
Phase 4

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Overview

The purpose of this study is to gather information on methocarbamol as a pain management treatment for ventral or inguinal hernia repair.

Methocarbamol has been part of the pain management treatment for both inpatient and outpatient procedures at Prisma Health. This study will compare the outcomes of patients who receive methocarbamol, those who receive the standard opioid pain management treatment, and those who receive methocarbamol plus the standard opioid pain management treatment.

Participants will be randomized into one of the study groups listed below.

Primary ventral hernia repair or inguinal hernia repair:

Group 1: standard opioid after surgery Group 2: methocarbamol after surgery

Open or robotic ventral hernia repair outpatient:

Group 1: standard opioid after surgery Group 2: standard opioid plus methocarbamol after surgery

Open or robotic ventral hernia repair inpatient:

Group 1: standard opioid at discharge Group 2: standard opioid plus methocarbamol at discharge

A total of 200 participants will be included in the study.

Participation will last for about 30 days after surgery.

Eligibility

Inclusion Criteria:

  • >18 y/o
  • Patients undergoing open primary ventral hernia repair (group 1)
  • Patients undergoing inguinal hernia repair (open, laparoscopic, or robotic; group 2)
  • Patients undergoing open incisional hernia repair (group 3)
  • Robotic repair ventral or incisional hernias (group 4)
  • Given consent for randomization

Exclusion Criteria:

  • <18 y/o
  • Pregnancy
  • Chronic opioid users

Study details
    Ventral Hernia
    Inguinal Hernia

NCT05388929

Prisma Health-Upstate

20 August 2025

FAQs

Learn more about clinical trials

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A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

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The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

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Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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