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Percutaneous Vertebroplasty Using Rotary Cutter for Bone Metastases

Percutaneous Vertebroplasty Using Rotary Cutter for Bone Metastases

Recruiting
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Phase N/A

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Overview

Percutaneous vertebroplasty has been applied widely to treat bone metastases. The injected cement may strengthen the affected bone to prevent pathological fractures and relieve the pain. Moreover, the thermal reaction (70°C) due to polymerisation of cement also contributes to tumour destruction. The cement dose and diffusion pattern may be significant factors for the treatment efficacy, which can be affected by the inner pressure of the metastases. The investigators will apply a rotary cutter to destroy the structure of metastases to alleviate the pressure in the metastases. Then, more cement will be injected, which may effectively interdigitates with the surrounding bone and generate more thermo to kill the tumor cells.

Eligibility

Inclusion Criteria:

  1. Imaging-proven and pathology-proven metastases
  2. Intractable pain with neurologic dysfunction

Exclusion Criteria:

  1. Poor general condition without tolerance of surgery

Study details
    Metastasis

NCT04017728

Li Min

27 January 2024

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