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Role of Lung Function for Exercise Capacity in Well-trained Individuals

Role of Lung Function for Exercise Capacity in Well-trained Individuals

Recruiting
18-39 years
All
Phase N/A

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Overview

The purpose of the project is to investigate exercise performance in humans following prolonged inhalation of beta2-agonists vilanterol + fluticasone furoate or indacaterol + mometasone furoate

Eligibility

Inclusion Criteria:

  • Age 18-39
  • Physically active > 5 h weekly
  • Maximal oxygen consumption classified as high or very high

Exclusion Criteria:

  • Diagnosed with severe asthma and been in treatment with long-acting beta2-agonist/corticosteroid
  • ECG abnormality
  • ACQ score > 1.5
  • Severe bronchial hyperreactivity as determined by mannitol test
  • FEV1/FVC ratio < 0.7 determined with spirometry
  • Chronic illness determined to be a potential risk for participant during study
  • In chronic treatment with medication that may interfere with study results
  • Pregnancy
  • Smoker
  • Blood donation during the past 3 months

Study details
    Exercise Performance

NCT06077019

Morten Hostrup, PhD

27 January 2024

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