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PD-1 Combined With Pyrotinib for Chemotherapy Failure HER2 Insertion Mutation Advanced NSCLC

PD-1 Combined With Pyrotinib for Chemotherapy Failure HER2 Insertion Mutation Advanced NSCLC

Recruiting
18-75 years
All
Phase 2

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Overview

The purpose of this study is to assess the safety and effectiveness of PD-1 Combined With Pyrotinib for First-line chemotherapy failed HER2 Insertion Mutation Positive Advanced Non-small Cell Lung Cancer

Eligibility

Inclusion Criteria:

  • Advanced non-small cell lung cancer confirmed by histology or cytology
  • HER2 insertion mutation-positive
  • Failure with first-line standard chemotherapy
  • with measurable lesions.

Exclusion Criteria:

  • no measurable tumor lesions
  • Patients received PD-1 or Pyrotinib before

Study details
    HER2 Insertion Mutation Positive Advanced NSCLC

NCT04144569

Yongchang Zhang

27 January 2024

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