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Clinical Outcomes in HIV With Comorbidities

Clinical Outcomes in HIV With Comorbidities

Recruiting
18 years and older
All
Phase N/A

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Overview

Multi-arm, non-randomized, quality of life

Description

This is a prospective, longitudinal, observational study, performed at a Co-morbidities clinic for PLWH. PLWH with one or more co-morbidities receiving anti-retroviral therapy (ART) will be analyzed for their prevalence and incidence of developing renal, metabolic, hepatic and bone diseases. All participants will be assessed at baseline and followed up for one year, or until change in ART regimen, whichever earlier.

Eligibility

Inclusion Criteria:

  1. HIV antibody positive
  2. Age above 18 years
  3. Diagnosis of one or more co-morbidities, including hypertension, diabetes, dyslipidemia, chronic kidney disease, chronic liver disease, and cardiovascular diseases
  4. Receiving ART regimen, which consists of B/F/TAF, or 1-2 NRTI(s), plus another anti-retroviral drug, including INSTI other than bictegravir, NNRTI, or protease inhibitor

Exclusion Criteria:

  1. Recent diagnosis of AIDS within 6 months
  2. Recent hospitalization for management of acute medical problems within 6 months
  3. Receiving ART regimens other than the combinations listed in Inclusion Criteria

Study details
    Hiv

NCT05824130

Grace Lui

27 January 2024

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