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Child Healthcare at MATER - Pediatric Study

Child Healthcare at MATER - Pediatric Study

Recruiting
18 years and older
Female
Phase N/A

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Overview

The objective of this project is to implement and evaluate a group model of well child care for mothers in treatment for opioid use disorder and their children that addresses the specific health needs and concerns of opioid-exposed infants, is trauma informed, and is embedded within a maternal opioid use disorder treatment program. 108 mother-infant dyads will be randomized 1:1 to group well child care or individual well child care, and followed over an 18 month period. Qualitative and quantitative data will be collected at multiple time points. The efficacy of group well child care to improve health and healthcare-related outcomes will be evaluated.

Description

This is a single-site cluster randomized controlled trial. Over an 18-month period, 108 pregnant women receiving treatment for opioid use disorder will be identified, screened, and enrolled into the study. Beginning with the birthdate of the first infant born in the study, 18 consecutive 1-month birth intervals will be randomized in a 1:1 ratio to one of two study arms: (1) group well child care or (2) individual well child care. Nine birth clusters will be randomized to individual well child care(control arm) and nine birth clusters will be randomized to group well child care(intervention arm), with concealment of randomization from enrolled participants until they give birth. All study participants will be included in the study until their child is approximately 18 months of age. All study participants will have a total of 5 assessment visits with research personnel; visits will occur immediately following enrollment into the study (baseline), prior to the participant's child turning 1 month of age, and within 4 weeks of the participant's child turning 6, 12, and 18 months of age. The efficacy of group well child care to improve health and healthcare-related outcomes will be evaluated.

Eligibility

Inclusion Criteria:

  • at least 28 weeks pregnant or less than 2 weeks postpartum
  • receiving treatment for opioid use disorder
  • ability to read and speak English
  • plans to parent infant after delivery
  • intent to seek pediatric care within Nemours/Thomas Jefferson University system
  • intent to remain in the Philadelphia area for the next 2 years

Exclusion Criteria:

  • inability to speak English
  • plans to move outside of the Philadelphia area in the next 2 years
  • plans to not parent infant after delivery
  • plans to seek pediatric care outside of the Nemours/Thomas Jefferson University System
        Following a live birth, participants will remain eligible to continue in the study unless
        the mother or infant experiences the following: gestational age at time of delivery less
        than or equal to 32 weeks or illness or clinical complication warranting prolonged
        hospitalization after delivery.

Study details
    Opioid Use Disorder

NCT05488379

Thomas Jefferson University

27 January 2024

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