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Reflex Excitability in Post-stroke Stiff-Knee Gait

Reflex Excitability in Post-stroke Stiff-Knee Gait

Not Recruiting
18 years and older
All
Phase N/A

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Overview

The purpose of this study is to examine the reflex excitability of the rectus femoris in individuals with and without post-stroke Stiff-Knee gait. We use electrical stimulation of the peripheral nerve innervating the rectus femoris for a well-controlled reflex stimulus. We are investigating whether reflex excitability of the rectus femoris correlates with gait kinematics.

Description

The purpose of this study is to investigate the role of hyperreflexia in post-stroke Stiff-Knee gait function. In one aim,

Eligibility

Inclusion criteria:

  • Aged at least 18
  • Premorbidly independent
  • If post-stroke, mild to moderate impairment determined by standard practices per the physical therapist
  • Able to continuously walk for 30 minutes
  • If post-stroke, reduced knee flexion during walking relative to unimpaired side
  • If post-stroke, hemiparesis
  • Ability to provide informed consent

Exclusion criteria:

  • No history of serious lower limb musculoskeletal injury
  • No functionally relevant osteoarthritis and weight-bearing restrictions
  • No functionally relevant polyneuropathy
  • No functionally relevant cognitive impairment
  • No functionally relevant vision impairment

Study details
    Stroke
    Chronic Stroke
    Gait
    Hemiplegic
    Gait
    Spastic
    Gait Disorder
    Sensorimotor
    Gait Disorders
    Neurologic
    Walking
    Difficulty

NCT04947865

MetroHealth Medical Center

30 January 2026

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