Overview

This prospective, single-institution, observational study explores disease outcomes and toxicities in subjects with gastrointestinal malignancies and sarcoma (bone and soft tissue) who are being treated with standard-of-care therapies including radiotherapy.

Recent advances in treatment approaches affected disease outcomes and toxicities. Prospective monitoring of disease outcomes and toxicities using standardized assessments will provide information about recent changes in the standard of care and further refine treatment approaches and prospective clinical trial design.

Eligibility

Inclusion Criteria

        In order to participate in this study a subject must meet all of the eligibility criteria
        outlined below.
          1. Subject is willing and able to provide written informed consent to participate in the
             study and HIPAA authorization for the release of personal health information. Subjects
             are willing and able to comply with study procedures based on the judgment of the
             investigator or protocol designer.
          2. Age ≥ 18 years at the time of consent.
          3. Histological, cytological, or radiographic evidence/confirmation of a gastrointestinal
             malignancy or sarcoma.
          4. Females with childbearing potential and male subjects with fathering potential are
             allowed to participate in this study.
        Exclusion Criteria
        All subjects meeting any exclusion criteria at baseline will be excluded from study
        participation.
          1. Inability or unwillingness to provide informed consent
          2. Patients who state they do not expect to be available or willing to follow up at
             expected intervals post-treatment