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Transoral Robotic Surgery in Treating Patients With Benign or Malignant Tumors of the Head and Neck

Transoral Robotic Surgery in Treating Patients With Benign or Malignant Tumors of the Head and Neck

Recruiting
18 years and older
All
Phase N/A

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Overview

This pilot clinical trial studies transoral robotic surgery (TORS) in treating patients with benign or malignant tumors of the head and neck. TORS is a less invasive type of surgery for head and neck cancer and may have fewer side effects and improve recovery

Description

To conduct a pilot single-arm study to assess transoral robotic surgery (TORS) for oral and laryngopharyngeal benign and malignant lesions using the Da Vinci Robotic Surgical System.

Eligibility

Inclusion Criteria:

  • Patient must present with indications for diagnostic or therapeutic approaches for benign and/or malignant diseases of the oral cavity or laryngopharynx (including the neoplastic lesions of the tongue, tongue base, retromolar trigone, tonsils, palate, posterior and lateral pharynx, glottic, supraglottic and subglottic larynx)
  • Patients must have adequate transoral exposure of the oral cavity and laryngopharynx for TORS instrumentation
  • Written informed consent and/or Consent waiver by institutional review board (IRB)

Exclusion Criteria:

  • Unexplained fever and/or untreated, active infection
  • Patient pregnancy
  • Previous head and neck surgery that would preclude transoral/robotic procedures. This is at the investigator's discretion. This is not an exclusion criterion for the non-surgical arm.
  • The presence of medical conditions contraindicating general anesthesia or transoral surgical approaches
  • Inability to grant informed consent
  • INTRAOPERATIVE EXCLUSION CRITERIA:
  • Inability to adequately visualize anatomy to perform the diagnostic or therapeutic surgical approach transorally

Study details
    Recurrent Adenoid Cystic Carcinoma of the Oral Cavity
    Recurrent Mucoepidermoid Carcinoma of the Oral Cavity
    Recurrent Squamous Cell Carcinoma of the Hypopharynx
    Recurrent Squamous Cell Carcinoma of the Larynx
    Recurrent Squamous Cell Carcinoma of the Lip and Oral Cavity
    Recurrent Verrucous Carcinoma of the Larynx
    Recurrent Verrucous Carcinoma of the Oral Cavity
    Stage 0 Hypopharyngeal Cancer
    Stage 0 Laryngeal Cancer
    Stage 0 Lip and Oral Cavity Cancer
    Stage I Adenoid Cystic Carcinoma of the Oral Cavity
    Stage I Mucoepidermoid Carcinoma of the Oral Cavity
    Stage I Squamous Cell Carcinoma of the Hypopharynx
    Stage I Squamous Cell Carcinoma of the Larynx
    Stage I Squamous Cell Carcinoma of the Lip and Oral Cavity
    Stage I Verrucous Carcinoma of the Larynx
    Stage I Verrucous Carcinoma of the Oral Cavity
    Stage II Adenoid Cystic Carcinoma of the Oral Cavity
    Stage II Mucoepidermoid Carcinoma of the Oral Cavity
    Stage II Squamous Cell Carcinoma of the Hypopharynx
    Stage II Squamous Cell Carcinoma of the Larynx
    Stage II Squamous Cell Carcinoma of the Lip and Oral Cavity
    Stage II Verrucous Carcinoma of the Larynx
    Stage II Verrucous Carcinoma of the Oral Cavity
    Stage III Adenoid Cystic Carcinoma of the Oral Cavity
    Stage III Mucoepidermoid Carcinoma of the Oral Cavity
    Stage III Squamous Cell Carcinoma of the Hypopharynx
    Stage III Squamous Cell Carcinoma of the Larynx
    Stage III Squamous Cell Carcinoma of the Lip and Oral Cavity
    Stage III Verrucous Carcinoma of the Larynx
    Stage III Verrucous Carcinoma of the Oral Cavity
    Stage IV Squamous Cell Carcinoma of the Hypopharynx
    Stage IVA Adenoid Cystic Carcinoma of the Oral Cavity
    Stage IVA Mucoepidermoid Carcinoma of the Oral Cavity
    Stage IVA Squamous Cell Carcinoma of the Larynx
    Stage IVA Squamous Cell Carcinoma of the Lip and Oral Cavity
    Stage IVA Verrucous Carcinoma of the Larynx
    Stage IVA Verrucous Carcinoma of the Oral Cavity
    Stage IVB Adenoid Cystic Carcinoma of the Oral Cavity
    Stage IVB Mucoepidermoid Carcinoma of the Oral Cavity
    Stage IVB Squamous Cell Carcinoma of the Larynx
    Stage IVB Squamous Cell Carcinoma of the Lip and Oral Cavity
    Stage IVB Verrucous Carcinoma of the Larynx
    Stage IVB Verrucous Carcinoma of the Oral Cavity
    Stage IVC Adenoid Cystic Carcinoma of the Oral Cavity
    Stage IVC Mucoepidermoid Carcinoma of the Oral Cavity
    Stage IVC Squamous Cell Carcinoma of the Larynx
    Stage IVC Squamous Cell Carcinoma of the Lip and Oral Cavity
    Stage IVC Verrucous Carcinoma of the Larynx
    Stage IVC Verrucous Carcinoma of the Oral Cavity
    Tongue Cancer

NCT01473784

Ohio State University Comprehensive Cancer Center

27 January 2024

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