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Implementation of Prevention and Intervention of Maternal Perinatal Depression to Strengthen Maternal and Child Health

Implementation of Prevention and Intervention of Maternal Perinatal Depression to Strengthen Maternal and Child Health

Recruiting
Female
Phase N/A

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Overview

IMPRINT strengthens maternal and child health by screening, treating and preventing maternal perinatal depression, the most common complication of pregnancy and the child's first 1000 days. It is associated with poor pregnancy outcome and perinatal mortality and has adverse consequences on physical and mental development of the child. Yet, only 7-28% of women with perinatal depression worldwide receive appropriate evidence-based care. This is astounding given that the need of investing on mental health is widely recognized and low-intensity interventions not requiring costly mental health professionals have been shown to be effective.

IMPRINT improves the effectiveness, reliability, safety, appropriateness, equity and efficiency of routine health care provided for the mother and the child during the child's first 1000 days of life. The investigators 1) have adapted into the gender-, country-, and cultural-context an existing evidence-based, low-intensity pregnancy intervention targeting maternal perinatal depression (online CBT-based therapy) (iloodottaa.fi); 2) test in cluster-randomised trial the short- and long-term efficacy of the intervention in women who report clinically relevant, subthreshold or more severe symptoms in an early pregnancy depression screen; 3) study biological, psychological and social determinants of depressive symptom severity, comorbidities and response to interventions. The study recruits women from 58 antenetal clinics in the cities of Helsinki, Vantaa, Keski-Uusimaa, Kuopio and Lohja and aims at recruiting 500 women to the intervention and 500 women to the control arms.

Eligibility

Inclusion Criteria:

  • EPDS screen result of 10 or more
  • Agreed to be invited for the intervention during the screening phase

Exclusion Criteria:

  • Active suicidality
  • Presence of severe mental disorder
  • Concurrent use of psychotropic medication / concurrently under psychosocial treatment for mental disorder

Study details
    Perinatal Depression

NCT04069091

Katri Räikkönen

27 January 2024

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