Overview
The overarching goal of the ARCH Survey is to establish a prospective longitudinal pregnancy surveillance study in Lusaka, Zambia, to precisely characterize the pregnancy rate and outcomes of women of reproductive age prior to, during, and following pregnancy and to investigate the structural, sociodemographic, and clinical covariates that contribute to adverse outcomes in each reproductive epoch.
Description
The overall purpose of this study is to better understand the health and well-being of women before and after they become pregnant and of their infants. This information will contribute to the understanding of the health needs of women and their children, which may help doctors provide mothers and children with better care in the future.
Participants in this study will be visited four times a year (every 3 months) for up to three years in total. At each visit a review of their medical records, a brief physical exam and urine pregnancy test will be conducted. Participants will also answer survey questions and self-collect vaginal swabs for future testing. We will enroll up to 5,500 women and include any infants that are born to them during their study participation.
Eligibility
We will initially obtain verbal consent from the head of household (HoH), defined as an
available adult (> 18 years old) who is able to provide information about household
composition for pre-screening purposes. We will then identify potentially eligible women of
reproductive age within each household and invite them to complete study screening
procedures.
Women of reproductive age eligibility criteria
Inclusion criteria:
- Verbal consent obtained from head-of-household
- 15-49 years of age and a member of household in the catchment area
- Willing and able to provide written informed consent or assent with next-of-kin
consent
- Willing to undergo study procedures
Exclusion criteria:
Any other condition (social or medical) that, in the opinion of the study staff, would make
participation unsafe or complicate data interpretation. Study staff may note physical,
psychological, or social conditions not explicitly stated in the eligibility criteria that
could make some women poor candidates for study participation.