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Left Atrial FLUTter: a Comparison of Ablation Guided by High-density MApping and Empirical LINEar Ablation.

Recruiting
18 years of age
Both
Phase N/A

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Overview

Unicenter, 1:1 randomized, open-labelled clinical trial comparing left atrial flutter ablation using high density mapping or strict lineal ablation. Main outcome: arrhythmia recurrences over 1 year follow-up with daily 1-lead 30 seconds ECG samples.

Eligibility

Inclusion criteria

  • Left atrial flutter1 inducible during electrophysiological evaluation.
  • Clinical indication for ablation: a) symptoms (palpitations, dizziness, syncope, breathlessness, derangement, heart failure), tachymiopathy, b) poor heart rate control, or c) recurrence after electrical cardioversion or failure of one antiarrhythmic drug.
  • Informed consent.
    1. Patients will be enrolled if LAFL is clinically suspected but finally randomized if this mechanism is established by electrophysiologic evaluation according to the criteria stated above.

Exclusion criteria

  • Previous ablation of LAFL.
  • Previous linear ablation in the LA except for pulmonary vein isolation.
  • Absolute contraindication for oral anticoagulation.
  • Stroke or acute coronary syndrome less than 3 months before ablation.
  • Complex congenital heart disease.

Study details

Arrhythmias, Cardiac

NCT05063032

Hospital Universitario La Paz

27 January 2024

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