Overview
The aim of the current study is to investigate and compare the effectiveness of probiotic supplementation and tDCS stimulation on risky decision-making related to food choices in overweight people. Considering the relatively established communication and interaction between the gut-brain-microbiome axis, the investigators expect that transcranial direct current stimulation and probiotic supplementation can both improve decision-making (decrease risky and impulsive decisions) and increase self-control in overweight people.
Eligibility
Inclusion Criteria:
- BMI over 25
- Higher than normal fat level
Exclusion Criteria:
- Pregnancy
- Breastfeeding
- Smoking more than 10 cigarettes a day
- Excessive consumption of alcohol
- Suffering from chronic cardiovascular and kidney diseases
- Chronic digestive diseases such as celiac disease,
- Chronic inflammatory bowel diseases such as colitis, intestinal surgery, cancer, etc.
- Suffering from acute and chronic diarrhea in the last one month
- Taking antibiotics in two months before the start of the study,
- Continuous use of prebiotic and probiotic products and drugs in one month before the start of the intervention
- Frequent use of antibiotics during the last month before the start of the intervention
- Taking weight loss medications and following a special slimming diet in the last 3 months before the intervention.
- History of epilepsy and seizures, stroke,
- Use of pacemaker
- Presence of metal implanted in the scalp or brain,
- Presence of skin lesions at the tDCS stimulation site, and history of head injury or brain surgery.
- Brain disorders and long-term and chronic use of neuropsychiatric drugs.