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Survival, Quality of Life and Resectability in Locally Advanced Pancreatic Cancer

Survival, Quality of Life and Resectability in Locally Advanced Pancreatic Cancer

Recruiting
18 years and older
All
Phase N/A

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Overview

This study aims to assess overall survival, quality of life and resection rates in locally advanced pancreatic cancer

Description

This is a multicenter pragmatic prospective observational study including Nordic hospitals treating patients with borderline resectable and locally advanced pancreatic cancer. Eligibility will be assessed at regional multidisciplinary tumor boards. Patients with borderline resectable and locally advanced (non-endocrine) pancreatic cancer according to the National Comprehensive Cancer Network (NCCN) and the International Study Group of Pancreatic Surgery (ISGPS) are eligible for inclusion. The study is observational. Quality of life will be assessed in all study participants. The primary outcomes are exploration rates, resection rates and overall survival.

Eligibility

Inclusion Criteria:

  • Confirmed or suspected invasive pancreatic primary tumor
  • Tumor classified as borderline resectable or locally advanced disease according to NCCN guidelines

Exclusion Criteria:

  • Suspected endocrine tumor
  • Suspected non-pancreatic periampullary tumor
  • Distant metastasis
  • Age < 18 years
  • Patient unable to understand verbal or written information interfering with informed consent or treatment
  • Mental or organic disorder interfering with informed consent or treatments

Study details
    Pancreas Cancer
    Pancreas Neoplasm
    Pancreas Disease
    Pancreas Adenocarcinoma
    Surgery
    Chemotherapy Effect
    Quality of Life
    Locally Advanced Pancreatic Adenocarcinoma
    Borderline Resectable Pancreatic Adenocarcinoma

NCT05356039

Umeå University

27 January 2024

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