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Rehabilitation for Survivors of Out-of-hospital Cardiac Arrest

Rehabilitation for Survivors of Out-of-hospital Cardiac Arrest

Recruiting
18-65 years
All
Phase 4

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Overview

This study is a parallel group multicentre investigator-initiated clinical randomised controlled superiority trial that will include a total of 214 survivors of OHCA.

Participants will to be randomized with a 1:1 allocation ratio to either a intervention consisting of a comprehensive initiated tailored rehabilitation intervention focusing on supporting RTW plus usual care compared to usual care alone.

Description

The ROCK trial is a two-arm multicentre investigator-initiated clinical randomised controlled superiority trial evaluating the effectiveness of a comprehensive individually tailored rehabilitation intervention focusing on supporting labour marked participation of survivors of out-of-hospital cardiac arrest compared to usual care, with primary endpoint measured after 12 months follow-up.

The overall aim of the ROCK trial is to evaluate the effectiveness of a comprehensive individually tailored multidisciplinary rehabilitation intervention for survivors of OHCA on RTW compared to usual care. The investigators hypothesize that the intervention will result in a higher-level labour marked attachment one year after hospital discharge in addition to increased health-related quality of life.

A full statistical analysis plan describing all details have been developed. In short, data from the national register on social transfer payments (DREAM database) will form the basis for the primary outcome. The primary outcome is labour market participation, defined as the proportion of employment vs. on social transfer payment, and the primary end point will be collected 12 months after hospital discharge.

Eligibility

Inclusion criteria:

  • All adult survivors with first time out-of-hospital cardiac arrest
  • Discharged from the Hospitals will be assessed eligible for inclusion

Exclusion criteria:

  • Survivors who prior to the cardiac arrest were not part of the labour force with at least two years until they are qualified to receive retirement state pensions
  • Patients that cannot understand and fulfil the study surveys (in Danish)
  • Patients with short witnessed cardiac arrests with return of spontaneous circulation estimated less than 4 minutes and immediate awakening without ICU treatment

Study details
    Cardiac Arrest
    Heart Arrest
    Cardiopulmonary Resuscitation
    Return to Work
    Return-to-work
    Rehabilitation
    Recovery of Function
    Cardiac Rehabilitation

NCT05173740

Rigshospitalet, Denmark

27 January 2024

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