Overview
Solid-organ transplant patients are at increased risk of infectious diseases. Among this population, infectious diseases may be life-threatening or lead to graft rejection. Their prevention is an important challenge. Despite specific national recommendations, vaccination is underutilized. That is why we propose a dedicated infectious diseases consultation during pre-kidney transplantation assessment.
Description
The main objective of this study is to impove vaccine coverage before kidney transplantation.
Enrollment was based on the waiting list for a kidney transplant. Patients newly listed are invited to participate by the transplant team (nephrology department) ; for those that are already registered, a notification letter is sent to their home.
All patients included must :
- complete a health questionnaire
- take a blood test at day 0 : viral, bacterial and parasitic serologies, QuantiFERON-TB
- take a chest X-ray and dental panoramic Patients randomized in interventional group will be seen in specific infectious diseases consultation at Clermont Ferrand Hospital. A letter of recommendations is sent to nephrologist for patients randomized in group control.
The primary study endpoint (immunization coverage) is evaluated at 6 months.
Eligibility
Inclusion Criteria:
- Patient over 18
- On the waiting list for kidney transplantation at Clermont-Ferrand
- Free and informed consent
- Affiliation to a social security system
Exclusion Criteria:
- Patient under 18
- Protected adults (individuals under guardianship by court order
- Pregnant and nursing women
- Prior graft (solid organs or hematopoietic stem cells)
- Absence of consent